EdenteV1, Main, Exploration, bibRecord, 000487

Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador—Rationale, Protocol, and Phase I Results of a Population-Based Survey: An Atahualpa Project-Ancillary Study

Identifieur interne : 000487 ( Main/Exploration ); précédent : 000486; suivant : 000488

Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador—Rationale, Protocol, and Phase I Results of a Population-Based Survey: An Atahualpa Project-Ancillary Study

Auteurs : Oscar H. Del Brutto [Équateur, États-Unis] ; Mark J. Sedler [États-Unis] ; Robertino M. Mera [États-Unis] ; Pablo R. Castillo [États-Unis] ; Elizabeth H. Cusick [États-Unis] ; Jadry A. Gruen [États-Unis] ; Kelsie J. Phelan [États-Unis] ; Victor J. Del Brutto [Équateur] ; Mauricio Zambrano [Équateur] ; David L. Brown [États-Unis]

Source :

International Journal of Vascular Medicine [ 2090-2824 ] ; 2014.

RBID : PMC:4217317

Abstract

Background. Little is known on the prevalence of peripheral artery disease (PAD) in developing countries. Study design. Population-based study in Atahualpa. In Phase I, the Edinburgh claudication questionnaire (ECQ) was used for detection of suspected symptomatic PAD; persons with a negative ECQ but a pulse pressure ≥65 mmHg were suspected of asymptomatic PAD. In Phase II, the ankle-brachial index will be used to test reliability of screening instruments and to determine PAD prevalence. In Phase III, participants will be followed up to estimate the relevance of PAD as a predictor of vascular outcomes. Results. During Phase I, 665 Atahualpa residents aged ≥40 years were enrolled (mean age: 59.5 ± 12.6 years, 58% women). A poor cardiovascular health status was noticed in 464 (70%) persons of which 27 (4%) had a stroke and 14 (2%) had ischemic heart disease. Forty-four subjects (7%) had suspected symptomatic PAD and 170 (26%) had suspected asymptomatic PAD. Individuals with suspected PAD were older, more often women, and had a worse cardiovascular profile than those with nonsuspected PAD. Conclusions. Prevalence of suspected PAD in this underserved population is high. Subsequent phases of this study will determine whether prompt detection of PAD is useful to reduce the incidence of catastrophic vascular diseases in the region.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4217317

DOI: 10.1155/2014/643589
PubMed: 25389500
PubMed Central: 4217317

Affiliations:

Le document en format XML

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 Results of a Population-Based Survey: An Atahualpa Project-Ancillary Study</title>
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 Results of a Population-Based Survey: An Atahualpa Project-Ancillary Study</title>
<author><name sortKey="Del Brutto, Oscar H" sort="Del Brutto, Oscar H" uniqKey="Del Brutto O" first="Oscar H." last="Del Brutto">Oscar H. Del Brutto</name>
<affiliation wicri:level="1"><nlm:aff id="I1">School of Medicine, Universidad Espíritu Santo-Ecuador, Guayaquil, Ecuador</nlm:aff>
<country xml:lang="fr">Équateur</country>
<wicri:regionArea>School of Medicine, Universidad Espíritu Santo-Ecuador, Guayaquil</wicri:regionArea>
<wicri:noRegion>Guayaquil</wicri:noRegion>
</affiliation>
<affiliation wicri:level="1"><nlm:aff id="I2">Air Center 3542, P.O. Box 522970, Miami, Fl 33152-2970, USA</nlm:aff>
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<author><name sortKey="Sedler, Mark J" sort="Sedler, Mark J" uniqKey="Sedler M" first="Mark J." last="Sedler">Mark J. Sedler</name>
<affiliation wicri:level="2"><nlm:aff id="I3">School of Medicine, Stony Brook University, Health Sciences Center, L-4 Room 158, Stony Brook, NY 11794, USA</nlm:aff>
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<author><name sortKey="Mera, Robertino M" sort="Mera, Robertino M" uniqKey="Mera R" first="Robertino M." last="Mera">Robertino M. Mera</name>
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<placeName><region type="state">Tennessee</region>
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<author><name sortKey="Castillo, Pablo R" sort="Castillo, Pablo R" uniqKey="Castillo P" first="Pablo R." last="Castillo">Pablo R. Castillo</name>
<affiliation wicri:level="2"><nlm:aff id="I5">Sleep Disorders Center, Mayo Clinic College of Medicine, 4500 San Pablo Road, Jacksonville, FL 32224, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Sleep Disorders Center, Mayo Clinic College of Medicine, 4500 San Pablo Road, Jacksonville, FL 32224</wicri:regionArea>
<placeName><region type="state">Floride</region>
</placeName>
</affiliation>
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<author><name sortKey="Cusick, Elizabeth H" sort="Cusick, Elizabeth H" uniqKey="Cusick E" first="Elizabeth H." last="Cusick">Elizabeth H. Cusick</name>
<affiliation wicri:level="2"><nlm:aff id="I3">School of Medicine, Stony Brook University, Health Sciences Center, L-4 Room 158, Stony Brook, NY 11794, USA</nlm:aff>
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<placeName><region type="state">État de New York</region>
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</affiliation>
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<author><name sortKey="Gruen, Jadry A" sort="Gruen, Jadry A" uniqKey="Gruen J" first="Jadry A." last="Gruen">Jadry A. Gruen</name>
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<country xml:lang="fr">États-Unis</country>
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<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
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<author><name sortKey="Phelan, Kelsie J" sort="Phelan, Kelsie J" uniqKey="Phelan K" first="Kelsie J." last="Phelan">Kelsie J. Phelan</name>
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<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>School of Medicine, Stony Brook University, Health Sciences Center, L-4 Room 158, Stony Brook, NY 11794</wicri:regionArea>
<placeName><region type="state">État de New York</region>
</placeName>
</affiliation>
</author>
<author><name sortKey="Del Brutto, Victor J" sort="Del Brutto, Victor J" uniqKey="Del Brutto V" first="Victor J." last="Del Brutto">Victor J. Del Brutto</name>
<affiliation wicri:level="1"><nlm:aff id="I6">Community Center, Villa Club Etapa Cosmos Mz 15 Villa 42, Atahualpa, Daule, Guayas, Ecuador</nlm:aff>
<country xml:lang="fr">Équateur</country>
<wicri:regionArea>Community Center, Villa Club Etapa Cosmos Mz 15 Villa 42, Atahualpa, Daule, Guayas</wicri:regionArea>
<wicri:noRegion>Guayas</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Zambrano, Mauricio" sort="Zambrano, Mauricio" uniqKey="Zambrano M" first="Mauricio" last="Zambrano">Mauricio Zambrano</name>
<affiliation wicri:level="1"><nlm:aff id="I6">Community Center, Villa Club Etapa Cosmos Mz 15 Villa 42, Atahualpa, Daule, Guayas, Ecuador</nlm:aff>
<country xml:lang="fr">Équateur</country>
<wicri:regionArea>Community Center, Villa Club Etapa Cosmos Mz 15 Villa 42, Atahualpa, Daule, Guayas</wicri:regionArea>
<wicri:noRegion>Guayas</wicri:noRegion>
</affiliation>
</author>
<author><name sortKey="Brown, David L" sort="Brown, David L" uniqKey="Brown D" first="David L." last="Brown">David L. Brown</name>
<affiliation wicri:level="4"><nlm:aff id="I7">Cardiovascular Division, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8086, St. Louis, MO 63110, USA</nlm:aff>
<country xml:lang="fr">États-Unis</country>
<wicri:regionArea>Cardiovascular Division, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8086, St. Louis, MO 63110</wicri:regionArea>
<placeName><region type="state">Missouri (État)</region>
<settlement type="city">Saint-Louis (Missouri)</settlement>
</placeName>
<orgName type="university">École de médecine (Université Washington de Saint-Louis)</orgName>
</affiliation>
</author>
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<series><title level="j">International Journal of Vascular Medicine</title>
<idno type="ISSN">2090-2824</idno>
<idno type="eISSN">2090-2832</idno>
<imprint><date when="2014">2014</date>
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<front><div type="abstract" xml:lang="en"><p><italic>Background</italic>
. Little is known on the prevalence of peripheral artery disease (PAD) in developing countries. <italic>Study design</italic>
. Population-based study in Atahualpa. In <italic>Phase I</italic>
, the Edinburgh claudication questionnaire (ECQ) was used for detection of suspected symptomatic PAD; persons with a negative ECQ but a pulse pressure ≥65 mmHg were suspected of asymptomatic PAD. In <italic>Phase II</italic>
, the ankle-brachial index will be used to test reliability of screening instruments and to determine PAD prevalence. In <italic>Phase III</italic>
, participants will be followed up to estimate the relevance of PAD as a predictor of vascular outcomes. <italic>Results</italic>
. During <italic>Phase I</italic>
, 665 Atahualpa residents aged ≥40 years were enrolled (mean age: 59.5 ± 12.6 years, 58% women). A poor cardiovascular health status was noticed in 464 (70%) persons of which 27 (4%) had a stroke and 14 (2%) had ischemic heart disease. Forty-four subjects (7%) had suspected symptomatic PAD and 170 (26%) had suspected asymptomatic PAD. Individuals with suspected PAD were older, more often women, and had a worse cardiovascular profile than those with nonsuspected PAD. <italic>Conclusions</italic>
. Prevalence of suspected PAD in this underserved population is high. Subsequent phases of this study will determine whether prompt detection of PAD is useful to reduce the incidence of catastrophic vascular diseases in the region.</p>
</div>
</front>
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<author><name sortKey="Escobedo De La Pe A, J" uniqKey="Escobedo De La Pe A J">J. Escobedo-de la Peña</name>
</author>
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<affiliations><list><country><li>Équateur</li>
<li>États-Unis</li>
</country>
<region><li>Floride</li>
<li>Missouri (État)</li>
<li>Tennessee</li>
<li>État de New York</li>
</region>
<settlement><li>Saint-Louis (Missouri)</li>
</settlement>
<orgName><li>École de médecine (Université Washington de Saint-Louis)</li>
</orgName>
</list>
<tree><country name="Équateur"><noRegion><name sortKey="Del Brutto, Oscar H" sort="Del Brutto, Oscar H" uniqKey="Del Brutto O" first="Oscar H." last="Del Brutto">Oscar H. Del Brutto</name>
</noRegion>
<name sortKey="Del Brutto, Victor J" sort="Del Brutto, Victor J" uniqKey="Del Brutto V" first="Victor J." last="Del Brutto">Victor J. Del Brutto</name>
<name sortKey="Zambrano, Mauricio" sort="Zambrano, Mauricio" uniqKey="Zambrano M" first="Mauricio" last="Zambrano">Mauricio Zambrano</name>
</country>
<country name="États-Unis"><noRegion><name sortKey="Del Brutto, Oscar H" sort="Del Brutto, Oscar H" uniqKey="Del Brutto O" first="Oscar H." last="Del Brutto">Oscar H. Del Brutto</name>
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<name sortKey="Brown, David L" sort="Brown, David L" uniqKey="Brown D" first="David L." last="Brown">David L. Brown</name>
<name sortKey="Castillo, Pablo R" sort="Castillo, Pablo R" uniqKey="Castillo P" first="Pablo R." last="Castillo">Pablo R. Castillo</name>
<name sortKey="Cusick, Elizabeth H" sort="Cusick, Elizabeth H" uniqKey="Cusick E" first="Elizabeth H." last="Cusick">Elizabeth H. Cusick</name>
<name sortKey="Gruen, Jadry A" sort="Gruen, Jadry A" uniqKey="Gruen J" first="Jadry A." last="Gruen">Jadry A. Gruen</name>
<name sortKey="Mera, Robertino M" sort="Mera, Robertino M" uniqKey="Mera R" first="Robertino M." last="Mera">Robertino M. Mera</name>
<name sortKey="Phelan, Kelsie J" sort="Phelan, Kelsie J" uniqKey="Phelan K" first="Kelsie J." last="Phelan">Kelsie J. Phelan</name>
<name sortKey="Sedler, Mark J" sort="Sedler, Mark J" uniqKey="Sedler M" first="Mark J." last="Sedler">Mark J. Sedler</name>
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   |texte=   Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador—Rationale, Protocol, and Phase I Results of a Population-Based Survey: An Atahualpa Project-Ancillary Study
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Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador—Rationale, Protocol, and Phase I Results of a Population-Based Survey: An Atahualpa Project-Ancillary Study

Prevalence, Correlates, and Prognosis of Peripheral Artery Disease in Rural Ecuador—Rationale, Protocol, and Phase I Results of a Population-Based Survey: An Atahualpa Project-Ancillary Study

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Abstract

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